Structural Requirements for PACSIN/Syndapin Operation during Zebrafish Embryonic Notochord Development
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چکیده
منابع مشابه
Structural Requirements for PACSIN/Syndapin Operation during Zebrafish Embryonic Notochord Development
PACSIN/Syndapin proteins are membrane-active scaffolds that participate in endocytosis. The structure of the Drosophila Syndapin N-terminal EFC domain reveals a crescent shaped antiparallel dimer with a high affinity for phosphoinositides and a unique membrane-inserting prong upon the concave surface. Combined structural, biochemical and reverse genetic approaches in zebrafish define an importa...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2009
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0008150